文献支持SLC26A3 Polyclonal Antibody_货号:E-AB-52774_多克隆抗体

Verified Samples in WB:Human hepatocellsular carcinoma,HepG2
Verified Samples in IHC:Human cervical cancer

WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Polyclonal

IgG

Fusion protein of human SLC26A3

SLC26A3

Chloride anion exchanger;CLD;Congenital chloride diarrhea;Down regulated in adenoma;Down regulated in adenoma protein;Down-regulated in adenoma;DRA;Protein DRA;S26A3;SLC26A3;Solute carrier family 26 member 3抗体

P40879

85 kDa

Refer to figures

Membrane.

0.6 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Antigen affinity purification

Cancer; Metabolism; Signal Transduction

Unconjugated

The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.SLC26A3 (Solute Carrier Family 26 Member 3) is a Protein Coding gene. Diseases associated with SLC26A3 include Diarrhea 1, Secretory Chloride, Congenital and Congenital Chloride Diarrhea. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Pancreatic secretion. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription cofactor activity. An important paralog of this gene is SLC26A4.