文献支持NQO1 Polyclonal Antibody_货号:E-AB-16011_多克隆抗体

Verified Samples in WB:Hela

WB 1:500-1:2000

Polyclonal

IgG

Synthetic peptide of human NQO1

NQO1

Azoreductase;Cytochrome b 5 reductase;DHQU;DIA 4;DIA4;Diaphorase (NADH/NADPH) (cytochrome b 5 reductase);Diaphorase (NADH/NADPH);Diaphorase 4;Dioxin inducible 1;DT diaphorase;DT-diaphorase;DTD;Menadione reductase;NAD(P)H dehydrogenase [quinone] 1;NAD(P)H dehydrogenase quinone 1;NAD(P)H menadione oxidoreductase 1 dioxin inducible;NAD(P)H quinone dehydrogenase 1;NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1;NAD(P)H:menadione oxidoreductase 1;NAD(P)H:Quinone acceptor oxidoreductase type 1;NAD(P)H:quinone oxidoreductase 1;NAD(P)H:quinone oxireductase;NMOR 1;NMOR I;NMOR1;NMORI;NQO 1;NQO1;NQO1;Phylloquinone reductase;QR 1;QR1;Quinone reductase 1抗体

P15559

27kDa

Cytoplasm.

0.3 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Metabolism; Signal Transduction

Unconjugated

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.