文献支持DIO1 Polyclonal Antibody_货号:E-AB-14929_多克隆抗体

Verified Samples in IHC:Human thyroid cancer,Human cervical cancer

IHC 1:100-1:300

Polyclonal

IgG

Recombinant protein of human DIDO1

DIDO1

BYE 1;BYE1;C20orf158;DATF 1;DATF-1;Death associated transcription factor 1;Death inducer obliterator 1;Death-associated transcription factor 1;Death-inducer obliterator 1;DIDO 1;DIDO 2;DIDO 3;DIDO1;DIDO1;DIDO2;DIDO3;DIO 1;DIO-1;DIO1;dJ885L7.8;DKFZp434P1115;FLJ11265;hDido 1;hDido1;KIAA0333;MGC16140抗体

Q9BTC0

Cytoplasm. Nucleus. Translocates to the nucleus after pro-apoptotic stimuli.

0.5 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Cell Biology; Epigenetics and Nuclear Signaling

Unconjugated

Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.