MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

(E/Z)-GO289

CAS No. : 694522-87-7

MCE 国际站：(E/Z)-GO289

产品活性：(E/Z)-GO289 是一种有效且选择性的酪蛋白激酶 2 (CK2) 抑制剂 (IC₅₀=7 nM)。(E/Z)-GO289 强烈延长昼夜节律周期。(E/Z)-GO289 表现出与细胞时钟功能相关的对癌细胞生长的细胞类型依赖性抑制。

研究领域：Cell Cycle/DNA Damage  |  Stem Cell/Wnt

作用靶点：Casein Kinase

In Vitro: (E/Z)-GO289 is a potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth.(E/Z)-GO289 shows an IC₅₀ of 13 μM for PIM2 and is >1000 times higher than that for CK2.
?(E/Z)-GO289 (3-9 μM; 2 days) strongly inhibits Caki-2, A498, and 769-P cells.
?(E/Z)-GO289 enables manipulation of clock protein phosphorylation and cancer cell growth.

相关产品：Bioactive Compound Library Plus  |  Cell Cycle/DNA Damage Compound Library  |  Kinase Inhibitor Library  |  Stem Cell Signaling Compound Library  |  Wnt/Hedgehog/Notch Compound Library  |  Anti-Cancer Compound Library  |  Anti-Aging Compound Library  |  Transcription Factor-Targeted Library  |  Cancer Stem Cells Compound Library  |  Membrane Protein-targeted Compound Library  |  Highly Selective Inhibitors Library  |  Serine/Threonine Kinase Inhibitor Library  |  LY294002  |  Silmitasertib  |  IWP-2  |  Emodin  |  Ellagic acid  |  D4476  |  Umbralisib  |  PF-670462 dihydrochloride  |  TBB  |  TMX-4116  |  Casein Kinase inhibitor A51  |  DMAT  |  PF-4800567  |  SR-3029  |  SSTC3  |  IC261  |  TAK-715  |  FPFT-2216  |  CKI-7 free base  |  SGC-CK2-1  |  CK1-IN-1  |  TTP 22  |  BTX161  |  AMG-548 dihydrochloride  |  BioE-1115  |  Hematein  |  TA-01  |  MRT00033659  |  CK2/ERK8-IN-1

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds