Ethylenediaminetetraacetic acid

价格： ￥350 - 665

品牌：MedChemExpress(MCE) 品牌认证

货号：HY-Y0682

产品详情

Ethylenediaminetetraacetic acid

CAS No. : 60-00-4

MCE 国际站：Ethylenediaminetetraacetic acid

产品活性：Ethylenediaminetetraacetic acid (EDTA) 是一种金属螯合剂 (与包括钙在内的二价和三价金属阳离子结合)。 Ethylenediaminetetraacetic acid 具有抗菌、抗炎、抗氧化、抗高钙血症和抗凝血活性。Ethylenediaminetetraacetic acid 可减少金属离子催化的蛋白质氧化损伤，并维持蛋白质纯化过程中的还原环境，常用作蛋白质的纯化和储存。Ethylenediaminetetraacetic acid 能够缓解肝脏的纤维化。Ethylenediaminetetraacetic acid 可以用于冠状动脉疾病和神经系统疾病的研究。

研究领域：Others | Anti-infection | Immunology/Inflammation

作用靶点：Biochemical Assay Reagents | Bacterial | SOD

In Vitro: Ethylenediaminetetraacetic acid has a strong bactericidal effect on the cell wall of P. aeruginosa and a. faecalis.
Ethylenediaminetetraacetic acid (0.005-0.01 M) has good heavy metal extraction in contaminated silty-clay-loam soil columns, can extract Pb, Cd and Zn in a concentration-dependent way with an extraction efficiency sequence of Pb > Cd > Zn.
Ethylenediaminetetraacetic acid (1.2 mM) enhances the activity of the CRE driving promoter by activating T-cell death-associated gene 8 (TDAG8) in HEK293T cells, thereby enhancing the production of cAMP in the cells.

In Vivo: Ethylenediaminetetraacetic acid (60 mg/kg; Intraperitoneal injection; Three times per week for three weeks) can reduce liver fibrosis, lipid peroxidation and liver inflammation in CCl₄ induced liver fibrosis rats, and has antioxidant and anti-inflammatory activities.