文献支持IL-1alpha 抗体 [Bamboo-2] (biotin)-IL-1alpha Antibody [Bamboo-2] (biotin)

免疫原 ：Recombinant mouse mature IL-1alpha.

保存条件 ：Stable for at least 1 year after receipt when stored at -20℃

保质期 ：1年

级别 ：科研级别

库存 ：100

供应商 ：艾美捷科技

宿主 ：小鼠

应用范围 ：E

抗体英文名 ：IL-1alpha Antibody [Bamboo-2] (biotin)

抗体名 ：IL-1alpha Antibody [Bamboo-2] (biotin)

规格 ：100ug

IL-1alpha 抗体 [Bamboo-2] (biotin)，IL-1alpha Antibody [Bamboo-2] (biotin)，IL-1alpha 抗体 [Bamboo-2] (biotin),IL-1alpha Antibody [Bamboo-2] (biotin)

产品名称：IL-1alpha 抗体 [Bamboo-2] (biotin)-IL-1alpha Antibody [Bamboo-2] (biotin)

产品货号：PSI-36-166-100ug

产品规格：100ug

背景资料：The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions, but also acts locally in a membrane-bound form by activating IL-1R1. Additionally, passive release of IL-1alpha upon cell death can trigger a sterile inflammatory response to dying cells. The cleavage of IL-1alpha is not mediated by caspase-1 and is not required for binding to IL-1R1. Recently it has been observed that all activators of the inflammasome NLRP3/NALP3 induce the simultaneous secretion of IL-1alpha and IL-1beta. Although most activators fully rely on the inflammasome for IL-1alpha secretion, some induce the processing and secretion of IL-1alpha in an inflammasome-independent manner.

保存建议：IL-1alpha 抗体 [Bamboo-2] (biotin)-IL-1alpha Antibody [Bamboo-2] (biotin)Stable for at least 1 year after receipt when stored at -20℃

应用类型：E

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