文献支持p53 抗体 [DO-7]-p53 Antibody [DO-7]

免疫原 ：Recombinant human wild type p53 expressed in E. coli was used as the immunogen for this antibody. Its epitope maps within the N-terminus portion (aa 20-25) of the p53 oncoprotein.

保存条件 ：Aliquot and Store at 2-8℃

保质期 ：1年

级别 ：科研级别

库存 ：100

供应商 ：艾美捷科技

宿主 ：小鼠

应用范围 ：WB, Flow, IHC, IF

抗体英文名 ：p53 Antibody [DO-7]

抗体名 ：p53 Antibody [DO-7]

规格 ：100ug

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产品名称：p53 抗体 [DO-7]-p53 Antibody [DO-7]

产品货号：PSI-33-218-100ug

产品规格：100ug

背景资料：This antibody is specific for a 53kDa protein, which is identified as p53 suppressor gene product. The large number of prolines in its amino acid sequence causes p53 to migrate slowly in SDS-PAGE, resulting in the amino acid content-estimated 43 kDa protein appearing larger than expected. DO-7 reacts with the mutant as well as the wild form of p53 under denaturing and non-denaturing conditions. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intra-tubular germ cell neoplasia.

保存建议：p53 抗体 [DO-7]-p53 Antibody [DO-7]Aliquot and Store at 2-8℃

应用类型：WB, Flow, IHC, IF

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