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免疫原 :Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAFK.
保存条件 :For short periods of storage (days) store at 4℃
保质期 :1年
级别 :科研级别
库存 :100
供应商 :艾美捷科技
宿主 :兔
应用范围 :E, WB
抗体英文名 :MAFK Antibody
抗体名 :MAFK Antibody
规格 :100ul
MAFK 抗体,MAFK Antibody,MAFK 抗体,MAFK Antibody
产品名称:MAFK 抗体-MAFK Antibody
产品货号:PSI-30-297-100ul
产品规格:100ul
背景资料:The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2. NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, PBGD and FECH. NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of bZIP proteins. Maf homodimers suppress transcription at NFE2 sites.The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 176000) and ferrochelatase (FECH; MIM 177000). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM].
保存建议:MAFK 抗体-MAFK AntibodyFor short periods of storage (days) store at 4℃
应用类型:E, WB
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入驻年限:11年