文献支持ET1607-2·Anti-CD63 Antibody [SY21-02]

靶点 ：CD63

浓度 ：1 mg/mL.

应用范围 ：WB,IHC-P

宿主 ：Rabbit

适应物种 ：Human

保质期 ：1年

供应商 ：Huabio

标记物 ：Non-conjugated

保存条件 ：Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

形态 ：Liquid

亚型 ：IgG

免疫原 ：Recombinant protein within Human CD63 aa 88-216 / 238.

规格 ：50μl/100μl

The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 (also known as LAMP-3, Melanoma-associated antigen ME491, TSPAN30, MLA1 and OMA81H) is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome.