M6211 麦格 环磷酸腺苷 cAMP

保存条件 ：见瓶身

保质期 ：见瓶身

英文名 ：环磷酸腺苷 cAMP

库存 ：999

供应商 ：麦飞生物

CAS号 ：60-92-4

规格 ：50mg

产品简介

CAS60-92-4

中文名称环磷酸腺苷

英文名称Adenosine 3',5'-cyclophosphate

别名Cyclic 3，5-monophosphate adenosine;Adenosine 3，5-cyclophosphate;Adenosine Cyclophosphate;3，5-AMP;环磷腺苷

纯度HPLC≥98%

分子式C10H12N5O6P

分子量329.21

外观（性状）白色至类白色粉末/White to off-white Powder

保存-20℃

有效期2 years

溶解性≥5mg/mL in Water

ECEINECS 200-492-9

MDLMFCD00005845

SMILESNC1=C2N=CN([C@@H]3O[C@]4([H])COP(O)(O[C@@]4([H])[C@H]3O)=O)C2=NC=N1

Note储备液建议分装冻存,避免反复冻融(-20℃,1个月);稀释后的工作液建议现用现配/It is recommended to freeze the stock solution in several small portions to avoid repeated freezing and thawing (- 20 ℃, 1 month); The working solution is recommended to be used immediately after dilution

规格50mg

单位瓶

使用本产品的案例（仅供参考）

UPLC-Q-TOF-HDMS 

UPLC conditions  

Chromatography was performed on an UPLC system with an autosampler at 4℃. The separation was carried out on an C18 column (1.7μm, 2.1 × 100 mm). The column temperature was maintained at 45℃. The analysis was performed with gradient elution using (A) acetonitrile, and (B) water with 0.1% formic acid as the mobile phase: 0–8 min, 1%–20% A; 8–11 min, 20%–30% A; 11–13 min, 30% –50% A; 13–16 min, 50%–99% A; 16–18 min, maintain 99% A; 18–19 min, 99%–1% A; held at 1% A for 3 min for equilibration of the column. Flow rate was set at 0.4 mL/min. The sample injection volume was 1μL. Throughout the analysis, all samples were kept at 4℃. 

Mass spectrometry conditions 

Mass Spectrometerwas connected to the UPLC system via electrospray ionization (ESI) interface. The capillary voltage and sample cone voltage, source offset voltage and the source temperature of positive and negativemodes were 2.5 kV, 60V, 80V, 120℃ and 2.0 kV, 40V, 60V, 130℃, respectively. The temperature of desolvation was 500℃. The cone and desolvation gas flow rates were 50 L/h and 800 L/h, respectively. The data acquisition rate was set at 0.2 s/scan, with a 0.1 s (0.02 interscan time) interscan delay. MS data was collected in centroid mode from 50 to 1200 Da. For accurate mass acquisition, a lock-mass ofleucine enkephalin was used to ensure accuracy through the whole MS analysis. 

来源文献：Ji H, Liu Y, He F, An R, Du Z. LC-MS based urinary metabolomics study of the intervention effect of aloe-emodin on hyperlipidemia rats. J Pharm Biomed Anal. 2018 Jul 15;156:104-115. doi: 10.1016/j.jpba.2018.04.015. Epub 2018 Apr 16. PMID: 29698861.