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保存条件 :RT/2-8℃/-20℃
保质期 :3年
英文名 :vitamin B12
库存 :999
供应商 :北京康瑞纳生物科技有限公司
CAS号 :68-19-9
规格 :1g
维生素B12 钴胺素(适用于细胞培养) 68-19-9 维生素B12 钴胺素(适用于细胞培养) 68-19-9
产品名称:维生素B12 钴胺素 68-19-9
产品编号:A3238
中文别称 维生素乙B12;青钴胺;维他命B12;Cyanocobalamin;Cyanocob(Ⅲ)alamin
英文别称 VitaminB12 CAS 68-19-9
分子式 C63H88CoN14O14P
分子量 1355.37
储存条件 2-8℃
有效期 3年
溶解性 2mg/ml in water
纯度 Approx:98%。
含量:≥98.0%
性状:深红色结晶粉末。无臭味,无味,对光敏感。
有吸湿性,在空气中能吸收12%水分。
其含水结晶在空气中稳定。
210~220℃时色变深,300℃不熔化。
其水溶液呈中性,在pH4.5~5时最稳定。
1g溶于约80ml水,溶于乙醇,不溶于丙.酮、氯仿和乙mi。
比旋光度-59°±9°(稀水溶液中)。
最大吸收波长(水中)278、361、550nm(A1%1cm115、204、64)。
最小致死量(大鼠,腹腔)1364mg/kg
性状 深红色结晶性粉末
包装 瓶
规格 1g5g25g
一般描述
维生素(B12)是一种水溶性维生素,通常称为钴胺素。乳制品、肉和蛋是这种维生素的主要来源。[1]
应用
维生素B12已用于:
用作Erdschreiber′s培养基组分[2]
用作杜氏改良Eagle′s培养基补充剂,用于从新生和成年大鼠中分离出的心室肌细胞[3]
雄性鹌鹑口服用药,以研究其在减少亚xi酸钠中毒体内负面影响方面的作用。[4]
生化/生理作用
维生素B12代谢为其甲基钴胺素活性形式。[4]恶性贫血患者体内可观测到维生素B12吸收受阻。[5]维生素B12对成红细胞发育至关重要。妊娠会导致维生素B12水平下降。[6]衰老会到维生素B12吸收减少。[7]它可充当脂肪、碳水化合物和蛋白质代谢中的辅酶。[4]它是细胞生长、遗传稳定性和体外存活必需的成分。参与支持一碳代谢。存在于许多经典和无血清配方中。
Vitamin B12 Cobalamin (for cell culture) 68-19-9
Product Name: Vitamin B12 Cobalamin 68-19-9
Product number: A3238
Also known as Vitamin B B12 in Chinese; Blue cobalt amine; Vitamin B12; Cyanocobalamin; Cyanocob (III) alamin
English alias VitaminB12 CAS 68-19-9
Molecular formula C63H88CoN14O14P
Molecular weight 1355.37
Storage conditions 2-8 ℃
Validity period of 3 years
Solubility 2mg/ml in water
Purity Approval: 98%.
Content: ≥ 98.0%
Appearance: Deep red crystalline powder. No odor, odorless, sensitive to light.
It has hygroscopicity and can absorb 12% moisture in the air.
Its water containing crystals are stable in the air.
Color darkens at 210-220 ℃ and does not melt at 300 ℃.
Its aqueous solution is neutral and most stable at pH 4.5-5.
1g is soluble in approximately 80ml of water, soluble in ethanol, and insoluble in ace.tone, chloroform, and ethylamine.
Specific rotation -59 ° ± 9 ° (in dilute aqueous solution).
The maximum absorption wavelengths (in water) are 278, 361, and 550nm (A1% 1cm115, 204, 64).
Minimum lethal dose (rat, abdominal cavity) 1364mg/kg
Appearance: Dark red crystalline powder
Packaging bottle
Specification 1g5g25g
General description
Vitamin (B12) is a water-soluble vitamin commonly known as cobalamin. Dairy products, meat, and eggs are the main sources of this vitamin. [1]
application
Vitamin B12 has been used for:
Used as a component of Erdschreiber's culture medium [2]
Used as a supplement to Du's modified Eagle's culture medium for isolated ventricular muscle cells from neonatal and adult rats [3]
Male quails were orally administered to study their role in reducing the negative effects of sodium sulfite poisoning in vivo. [4]
Biochemical/physiological effects
Vitamin B12 is metabolized into its active form of me.thylcobalamin. [4] Obstruction of vitamin B12 absorption can be ob.s
erved in patients with pernicious anemia. [5] Vitamin B12 is crucial for the development of red blood cells. Pregnancy can lead to a decrease in vitamin B12 levels. [6] Aging can lead to reduced absorption of vitamin B12. [7] It can act as a coenzyme in fat, carbohydrate, and protein metabolism. [4] It is an essential component for cell growth, genetic stability, and in vitro survival. Participate in supporting carbon metabolism. Exists in many classic and serum-free formulas
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