文献支持Purified 抗小鼠 CLEC-2 (CLEC1B) 抗体

供应商 ：齐源

库存 ：999

靶点 ：CLEC-2 (CLEC1B)

级别 ：CLEC-2 (CLEC1B) Antibody

目录编号 ：CLEC-2 (CLEC1B) Antibody

克隆性 ：单克隆

抗原来源 ：大鼠

保质期 ：CLEC-2 (CLEC1B) Antibody

抗体英文名 ：Purified anti-mouse CLEC-2 (CLEC1B) Antibody

抗体名 ：CLEC-2 (CLEC1B) Antibody

标记物 ：CLEC-2 (CLEC1B) Antibody

宿主 ：大鼠

适应物种 ：小鼠

免疫原 ：CLEC-2 (CLEC1B) Antibody

亚型 ：CLEC-2 (CLEC1B) Antibody

形态 ：CLEC-2 (CLEC1B) Antibody

应用范围 ：FC, WB

保存条件 ：2-8℃

浓度 ：0.5 mg/ml

规格 ：100 µg

Purified anti-mouse CLEC-2 (CLEC1B) Antibody详细如下：

Description ：CLEC-2, also known as CLEC1B and CLEC1B1, is C-type lectin-like receptor with a singlecytoplasmic YXXL sequence known as a hem-immunoreceptor tyrosine-based activation motif(hemITAM). CLEC-2 is highly expressed on resting platelets and megakaryocytes and at alower levels on several hematopoietic cells including monocytes, macrophages, dendritic cells,and granulocytes. The first ligand that was identified for CLEC-2 was the snake venom toxinrhodocytin; podoplanin has also been identified as an endogenous ligand for CLEC-2.Exposure of platelets to rhodocytin leads tyrosine phosphorylation of the ITAM-like motif andSyk-dependent platelet activation. CLEC-2 also functions as an activation receptor onmonoyctes and neutrophils to induce phagocytosis and proinflammatory cytokine production.

Verified Reactivity ：Mouse

Antibody Type ：Monoclonal

Host Species ：Rat

Immunogen ：RBL-2H3 cells stably expressing HA-tagged mouse CLEC2.

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation ：The antibody was purified by affinity chromatography.

Concentration ：0.5 mg/ml

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C.

Application ：FC - Quality tested、WB - Reported in the literature, not verified in house

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.