Purified 抗 STAT6 抗体

供应商 ：齐源

库存 ：999

靶点 ：STAT6

级别 ：STAT6 Antibody

目录编号 ：STAT6 Antibody

克隆性 ：单克隆

抗原来源 ：小鼠

保质期 ：STAT6 Antibody

抗体英文名 ：Purified anti-STAT6 Antibody

抗体名 ：STAT6 Antibody

标记物 ：STAT6 Antibody

宿主 ：小鼠

适应物种 ：人、小鼠

免疫原 ：STAT6 Antibody

亚型 ：STAT6 Antibody

形态 ：STAT6 Antibody

应用范围 ：WB, ICC, IP, ChIP

保存条件 ：2-8℃

浓度 ：0.5 mg/ml

规格 ：25 ug/100 ug

Purified anti-STAT6 Antibody详细如下：

Description ：STAT6 is a member of the signal transducer and activator of transcription (STAT) family,activating gene expression in response to IL-4 and IL-13 stimulation. Upon cytokine stimulation,the receptor is phosphorylated by the associated Janus Kinases (Jak), followed by recruitingcytoplasmic STAT6. The Y641 residue of STAT6 is, in turn, phosphorylated by Jak.Phosphorylated STAT6 forms homodimers, transclocates to the nucleus, and regulatestranscription of target genes. STAT6 plays crucial roles in differentiation of T helper 2 (Th2)cells, class switch of immunoglobulins in B cells, expression of cell surface markers such asMHC class II, and the development of allergic inflammation.

Verified Reactivity ：Human, Mouse

Antibody Type ：Monoclonal

Host Species ：Mouse

Immunogen ：Partial human STAT6 recombinant protein (678-847 aa)

Formulation ：This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation ：Affinity purified.

Concentration ：0.5 mg/ml

Storage & Handling ：Upon receipt, store undiluted between 2°C and 8°C.

Application ：WB - Quality tested、ICC, IP, ChIP - Verified

Recommended Usage ：Each lot of this antibody is quality control tested by Western blotting. For Western blotting, thesuggested use of this reagent is 0.5 - 2.0 µg per ml. For immunocytochemistry, a concentration of5.0 μg/ml is recommended. For immunoprecipitation, the suggested use of this reagent is 5.0 - 20μg per ml. For ChIP applications, the suggested use of this reagent is 1:50-1:100 by volume. It isrecommended that the reagent be titrated for optimal performance for each application.