NF κB P105/P50 Mouse mAb(4D11)

供应商 ：FLIGHT

库存 ：50μl/100μg

靶点 ：Monoclonal  

级别 ：/

目录编号 ：FLD-M-161

克隆性 ：单克隆

抗原来源 ：/

保质期 ：1year

抗体英文名 ：NF κB P105/P50 Mouse mAb(4D11)

抗体名 ：NF κB P105/P50 Mouse mAb(4D11)

标记物 ：/

宿主 ：鼠

适应物种 ：H, M

免疫原 ：/

亚型 ：/

形态 ：液体

应用范围 ：WB

保存条件 ：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

浓度 ：100μg/瓶

规格 ：50μl/100μl

Applications:          WB-Western blot     IHC-Immunochemistry       IF-Immunofluorescence     IP-Immunoprecipitation     ChIP-Chormatin Immunoprecipitation

Reactivity:
H-Human R-Rat M-Mouse Mk-Monkey Dg-Dog Ch-Chicken Hm-Hamster Rb-Rabbit Sh-Sheep Pg-Pig
 
Nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth.

WB:

Western blot analysis of 1)MCF7 Cell, 2) Mouse Brain Tissue  Lysate using NF κB P105/P50（FLD-M-161）Mouse Monoclonal mAb diluted at 1:1,000.