供应商 :齐源
库存 :999
靶点 :CD3ε
级别 :CD3ε Antibody
目录编号 :CD3ε Antibody
克隆性 :单克隆
抗原来源 :仓鼠
保质期 :CD3ε Antibody
抗体英文名 :Cyanine7 anti-mouse CD3ε Antibody-APC
抗体名 :CD3ε Antibody
标记物 :APC
宿主 :仓鼠
适应物种 :小鼠
免疫原 :CD3ε Antibody
亚型 :CD3ε Antibody
形态 :CD3ε Antibody
应用范围 :FC
保存条件 :2-8℃
浓度 :0.2 mg/ml
规格 :25 µg/100 µg
Cyanine7 anti-mouse CD3ε Antibody-APC详细如下:
Description :CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Igsuperfamily and primarily expressed on T cells, NK-T cells, and at different levels onthymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with theCD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCRsignal transduction, T cell activation, and antigen recognition by binding the peptide/MHCantigen complex.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Armenian Hamster
Immunogen :H-2K -specific mouse cytotoxic T lymphocyte clone BM10-37
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation :The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 underoptimal conditions.
Concentration :0.2 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 10 cells in100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Excitation Laser :Red Laser (633 nm)
该产品被引用文献
Application References(PubMed link indicatesBioLegend citation):
1. Leo O, et al. 1987. P. Natl. Acad. Sci. USA 84:1374. (IP, Activ, Block)
2. Kruisbeek AM, et al. 1991. In Current Protocols in Immunology. 3.12.1. (Activ)
3. Duke RC, et al. 1995. Current Protocols in Immunology. 3.17.1.
4. Salvadori S, et al. 1994. J. Immunol. 153:5176. (WB)
5. Payer E, et al. 1991. J. Immunol. 146:2536. (IF)
6. Jacobs H, et al. 1994. Eur. J. Immunol. 24:934. (CMCD)
7. Vossen ACTM, et al. 1995. Eur. J. Immunol. 25:1492. (Activ)
8. Henrickson M, et al. 1995. Transplantation 60:828. (Deplete)
9. Kinnaert P, et al. 1996. Transpl. Int. 9:386. (Deplete)
10. Han WR, et al. 1999. Transpl. Immunol. 7:207. (Deplete)
11. Miescher GC, et al. 1989. Immunol. Lett. 23:113. (Block)
12. Terrazas LI, et al. 2005. Intl. J. Parasitology. 35:1349. (Activ)
13. Ko SY, et al. 2005. J. Immunol. 175:3309.
14. Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC-F)
15. Tilley SL, et al. 2007. J. Immunol. 178:3208. (IHC-F)
16. Wang W, et al. 2007. J. Immunol. 178:4885. (Activ)
17. Xiao S, et al. 2007. J. Exp. Med. 204:1691.
18. Chappaz S, et al. 2007. Blood doi:10.1182/blood-2007-02-074245. (FC) PubMed.
19. Curtsinger JM, et al.2005. J. Immunol. 175:4392. PubMed
20. Guo Y, et al. 2008. Blood 112:480. PubMed
21. Kenna TJ, et al. 2008. Blood 111:2091.
22. Perchonock CE, et al. 2007. J. Immunol. 179:1768. PubMed
23. Perchonock GE, et al. 2006. Mol. Cell. Biol. 26:6005. PubMed
24. Kanaya T, et al. 2008. Am. J. Physiol. Gastrointest. Liver Physiol. 295:G273. PubMed
25. de Koning BA, et al. 2006. Int. Immunol. 18:941. PubMed
26. Schulteis RD, et al. 2008. Blood 295:G273. PubMed
27. Qi Q, et al. 2009. Blood 114:564. PubMed
28. Helmersson S, et al. 2013. Am J Pathol. 9440:123. Pubmed
29. Wu S, et al. 2014. Clin Vaccine Immunol. 21:156. PubMed
30. Yan J, et al. 2014. Vaccine. 32:2833. PubMed
31. Guiterrez DA, et al. 2014. Diaebetes. 63:3827. PubMed
32. Shi YF, et al. 1991. J Immunol. 146:3340. (Apop)
Product Citations:
1. Palacios-Arreola M, et al. 2017. Sci Rep. 10.1038/s41598-017-10135-1. PubMed
2. Saha D et al. 2017. Cancer cell. 32(2):253-267 . PubMed
3. Miao L, et al. 2020. Theranostics. 0.7625. PubMed
4. Zhou J, et al. 2019. Immunity. 50:403. PubMed
5. Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed
6. Mitroulis I et al. 2018. Cell. 172(1-2):147-161 . PubMed
7. Fu B et al. 2017. Immunity. 47(6):1100-1113 . PubMed
8. Meng J, et al. 2011. Biol Reprod. 85:254. PubMed
9. Wei H, et al. 2021. Malar J. 20:89. PubMed
10. Earnest JT, et al. 2021. Cell Reports. 35(1):108962. PubMed
11. Chikina AS, et al. 2020. Cell. 183:411. PubMed
12. Rao S, et al. 2017. Cell. 168(3):503-516.e12. PubMed