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供应商 :齐源
库存 :9999
靶点 :Adiponectin
级别 :Adiponectin (Acrp30) Antibody
目录编号 :Adiponectin (Acrp30) Antibody
克隆性 :单克隆
抗原来源 :小鼠
保质期 :Adiponectin (Acrp30) Antibody
抗体英文名 :Biotin anti-human Adiponectin (Acrp30) Antibody
抗体名 :Adiponectin (Acrp30) Antibody
标记物 :Adiponectin (Acrp30) Antibody
宿主 :小鼠
适应物种 :人
免疫原 :Adiponectin (Acrp30) Antibody
亚型 :Adiponectin (Acrp30) Antibody
形态 :Adiponectin (Acrp30) Antibody
应用范围 :ELISA Detection
保存条件 :2-8℃
浓度 :0.5 mg/ml
规格 :50 ug/500 ug
Biotin anti-human Adiponectin (Acrp30) Antibody详细如下:Description :Adiponectin, also referred as Acrp30, AdipoQ, apM1, and gelatin binding protein of 28 kD(GBP-28), is encoded by the ADIPOQ gene in humans. Adiponectin contains 244 amino acidswith a collagen-like domain at the N-terminal and a globular domain at the C-terminal. Theglobular domain can be proteolytically truncated forming the globular adiponectin(gAdiponectin). This globular domain resembles the structure of the complement C1q and theTNF-α superfamily. Adiponectin exists in a wide range of homo-oligomers: a low-molecularweight (LMW) trimer, a medium molecular weight (MMW) hexamer, and a high molecular weight(HMW) multimer with little or no interconversion between the forms. Females generally havehigher HMW than males in proportion and absolute amounts. Adiponectin has two receptors(adipoRs)-1 and -2. AdipoR1 mRNA is detectable in skeletal muscle, spleen, lung, heart,kidney, and liver. AdipoR2 is expressed in liver, but is also detectable in heart, lung, skeletalmuscle, and kidney.
Adiponectin plays an important role in carbohydrate and lipid metabolism. It promotes insulinsensitivity and protects cells from inflammation and apoptosis. It is also hypothesized to haveanti-atherogenic activity. Normal circulating adiponectin level ranges from 4-30 µg/mL.Adiponectin levels are inversely correlated with body mass index (BMI). Low serum level ofadiponectin is found in obesity, type 2 diabetes and those with coronary artery disease.Therefore, adiponectin serves as an important clinical biomarker for metabolic syndromes.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :Recombinant human Adiponectin
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation :The antibody was purified by affinity chromatography and conjugated with biotin under optimalconditions.
Concentration :0.5 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application :ELISA Detection - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, aconcentration range of 0.05-0.2 µg/ml is recommended. To obtain a linear standard curve, serialdilutions of Adiponectin protein ranging from 10,000 to 156 pg/ml are recommended for eachELISA plate. It is recommended that the reagent be titrated for optimal performance for eachapplication.
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入驻年限:5年