BioLegend 123411 APC anti-mouse CD21/CD35 (CR2/CR1)

库存 ：99

英文名 ：APC anti-mouse CD21/CD35 (CR2/CR1)

供应商 ：北京云肽生物科技有限公司

北京云肽生物科技有限公司作为BioLegend的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。

美国BioLegend公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend虽然成立的时间不长，但它聚集了一批来自PharMingen公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。BioLegend公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。

BioLegend 123411 APC anti-mouse CD21/CD35 (CR2/CR1)
产品简介：
产品品牌：BioLegend 
产品货号：123411
产品名称：BioLegend 123411 APC anti-mouse CD21/CD35 (CR2/CR1)
产品规格：25 µg

产品说明：
Clone  7E9 (See other available formats)
Regulatory Status  RUO
Other Names  CR2/CR1
IsotypeRat  IgG2a, κ

描述
CD21，也称为CR2（补体受体2）和C3d受体，结合C3d和iC3b。它也是EB病毒的受体。CD35，也称为CR1，结合C3b、iC3b、C4b和iC4b。CD21/CD35主要在B淋巴细胞、肥大细胞、滤泡树突状细胞、巨噬细胞和活化的粒细胞上表达。CD21/CD35与CD19和CD81形成B细胞抗原受体复合物的一部分，并参与信号转导。
CD21, also known as CR2 (complement receptor 2) and C3d receptor, binds C3d and iC3b. It is also a receptor of Epstein-Barr virus. CD35, also known as CR1, binds C3b, iC3b, C4b, and iC4b. CD21/CD35 is primarily expressed on B lymphocytes, mast cells, follicular dendritic cells, macrophages, and activated granulocytes. CD21/CD35 forms part of the B-cell antigen receptor complex with CD19 and CD81 and is involved in signal transduction.

Product Details
Isotype Control  APC Rat IgG2a, κ Isotype Ctrl
Verified Reactivity  Mouse
Antibody Type  Monoclonal
Host Species  Rat
Immunogen  CD35/CFA
Formulation  Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation  The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration  0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application  FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser  Red Laser (633 nm)

Antigen Details
Structure  145 kD/190 kD type I transmembrane glycoprotein
Distribution  B cells, follicular dendritic cells
Function  Signal transduction
Ligand/Receptor   
Associated with CD19/CD81. CD21 binds C3d, iC3b, and EBV; CD35 binds C3b, iC3b, C4b, and iC4b.
Cell Type  B cells, Dendritic cells
Biology Area  Cell Biology, Costimulatory Molecules, Immunology, Neuroinflammation, Neuroscience
Molecular Family  Adhesion Molecules, CD Molecules

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