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SDH-IN-3

CAS No. : 2805297-11-2

MCE 国际站：SDH-IN-3

产品活性：SDH-IN-3 是一种琥珀酸脱氢酶 (SDH) 抑制剂，IC₅₀ 为 7.6 μg/mL。SDH-IN-3 对 Nigrospora oryzae 表现出优异的抗真菌活性，EC₅₀ 为 1.9 μg/mL。SDH-IN-3 可用于抗感染研究。

研究领域：Anti-infection

作用靶点：Antibiotic  |  Fungal

In Vitro: SDH-IN-3(Compound T6) (40 μg/mL; 6-7 days) has in vivo protective and curative activities against rice infected with N.oryzae mycelia 81.5% and 43.0%, respectively.
SDH-IN-3 (0-40 μg/mL; 14-80 hours) significantly inhibits the growth of N.oryzae mycelia and hinders spore germination and germ tube elongation.
SDH-IN-3(0-20 μg/mL; 12-36 hours) affects the mycelium membrane integrity of N.oryzae mycelia by increasing cell membrane permeability and causing peroxidation of cellular lipids.

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