SU 16f,PDGFRβ抑制剂

保存条件 ：避光 -20°C储存

英文名 ：SU 16f

供应商 ：阿拉丁

CAS号 ：251356-45-3

规格 ：10mg, 25mg, 50mg, 5mg

产品介绍：A cell-permeable indolinone compound that acts as a potent, ATP site-targeting PDGFR inhibitor (IC50 = 10 nM against PDGFRβ), while affecting Flk-1/KDR/ VEGFR2, FGFR1, and EGFR only at much higher concentrations (IC50 = 0.14, 2.29, and >100 µM, respectively). Reported to selectively inhibit PDGFβ- over EGF-stimulated proliferation in EGFR-expressing NIH 3T3 cultures (IC50 = 0.11 and 21.9 µM, respectively) and exhibit much weaker potency against the proliferation of HUVEC cells upon FGF or VEGF stimulation (IC50 = 10 µM).更多产品详情请见阿拉丁官网，该产品链接：https://www.aladdin-e.com/zh_cn/S288019.html