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KDM5-C49 hydrochloride

CAS No. :

MCE 国际站：KDM5-C49 hydrochloride

产品活性：KDM5-C49 (KDOAM-20) hydrochloride 是一种有效和选择性的 KDM5 去甲基化酶抑制剂，抑制 KDM5A，KDM5B 和 KDM5C 的 IC₅₀ 值分别为 40 nM，160 nM 和 100 nM。KDM5-C49 hydrochloride 可用于癌症的研究。

研究领域：Epigenetics

作用靶点：Histone Demethylase

In Vitro: KDM5-C49 hydrochloride display poor permeability. Convert the carboxylate group of KDM5-C49 into an ethyl ester, to get a cell-permeable prodrug (KDM5-C70).

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