重组犬细小病毒VP2蛋白价格_品牌:xuanya-丁香通官网

库存：100

英文名：Recombinant CPV VP2 protein, His

CAS号：/

保质期：1年

供应商：上海烜雅生物科技有限公司

保存条件：2-8°C不超过一个月，-80°C不超过12个月

规格：100ug

重组犬细小病毒VP2蛋白相关信息：

英文名称	Recombinant CPV VP2 protein, His
中文名称	重组犬细小病毒VP2蛋白
别名	Capsid protein VP2; Coat protein VP2; Canine parvovirus; CAPSD_PAVC; Capsid protein VP2 · Canine parvovirus type 2 (CPV-2); Recombinant CPV2 VP2 protein, His
理论分子量	42kDa
性状	Lyophilized or Liquid
浓度	＞0.5 mg/ml
物种	CPV
序列	201-584/584
纯度	>95% as determined by SDS-PAGE
纯化方法	AC
内毒素	Not analyzed
表达系统	E.coli
活性	Not tested
标签	His
缓冲液	0 mM Tris-HCl (pH=8.0) with 150 mM NaCl.
保存条件	Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

重组犬细小病毒VP2蛋白

产品介绍：Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptor TFRC. This attachment induces virion internalization predominantly through clathrin-endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and nuclear localization signal(s). VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell. Intracytoplasmic transport involves microtubules and interaction between capsid proteins and host dynein. Exposure of nuclear localization signal probably allows nuclear import of capsids.

重组犬细小病毒VP2蛋白应用：仅供研究使用，不用于临床诊断！

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