文献支持人源化重组抗人HER2Fab片段抗体-400-001-GY3|Humanized Recombinant Anti-Human HER2 Fab fragment Antibody - 400-001-GY3

保存条件 ：Store vial at 2-8° C prior to opening.

保质期 ：1年

库存 ：100

供应商 ：艾美捷科技

宿主 ：该Humanized Recombinant Anti-Human HER2 Fab fragment Antibody - 400-001-GY3的详细信息查看Rockland提供的产品说明书。

抗体英文名 ：Humanized Recombinant Anti-Human HER2 Fab fragment Antibody - 400-001-GY3

规格 ：50ug

Humanized Recombinant Anti-Human HER2 Fab fragment Antibody - 400-001-GY3，人源化重组抗人HER2Fab片段抗体-400-001-GY3，人源化重组抗人HER2Fab片段抗体-400-001-GY3,Humanized Recombinant Anti-Human HER2 Fab fragment Antibody - 400-001-GY3

产品名称：人源化重组抗人HER2Fab片段抗体-400-001-GY3-Humanized Recombinant Anti-Human HER2 Fab fragment Antibody - 400-001-GY3

产品货号：400-001-GY3

产品规格：50ug

应用类型：ELISA,Flow Cytometry,Western Blot,

保存建议：人源化重组抗人HER2Fab片段抗体-400-001-GY3-Humanized Recombinant Anti-Human HER2 Fab fragment Antibody - 400-001-GY3Store vial at 2-8° C. Dilute only prior to immediate use.

背景资料：HER2 (human epidermal growth factor receptor 2) is a member of the epidermal growth factor receptor (HER/EGFR/ERBB) family. It is also called ERBB2, CD340 or proto-oncogene Neu. The protein is a receptor tyrosine kinase located on the plasma membrane of cells. Activation of the tyrosine kinase promotes cell proliferation and suppresses apoptosis. HER2 can dimerize with any other member of the ErbB family, which results in auto phosphorylation of tyrosine residues and activation of signal pathways. HER2 is over expressed in a significant proportion of cancer patients, resulting in an increased disease recurrence and poor prognosis. Therefore an early diagnosis of the HER2 status of the tumors is necessary to decide the appropriate treatment. Besides in breast cancer HER2 is over expressed in variety of different tumors. The over expression of HER2 makes it a target for immunotherapy of certain tumor patients. The antibody Trastuzumab (Herceptin) which recognizes HER2 was approved for the treatment of HER2 positive breast cancer patients in 1998. The original approval was for treatment of HER2 positive metastatic breast tumors. Later studies have shown that Herceptin is also beneficial for early stage HER2 positive tumor patients and it is approved as an adjuvant treatment. Additionally the antibody is now approved also for other HER2 positive tumors (metastatic gastric adenocarcinoma). This antibody is made from a humanized Fab fragment making it specific, efficient, and effective. Humanized Recombinant Anti-HER2 Fab fragment Antibody is useful for researchers interested in Cancer research.

点击：人源化重组抗人HER2Fab片段抗体-400-001-GY3-Humanized Recombinant Anti-Human HER2 Fab fragment Antibody - 400-001-GY3查看更详细产品说明，更多应用、储存、价格、货期等信息请致电027-59626688垂询艾美捷科技有限公司。更多Rockland公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。

Rockland成立于1962年，是一家老牌抗体原产企业，其位于美国费城郊区的农场保有近20种实验动物。Rockland公司为生命科学领域提供丰富的、高质量的抗体，包括载脂蛋白、细胞周期/凋亡、细胞因子、细胞信号蛋白、酶类、细胞外基质、转录因子(NFkB)和泛素（Ubiquitin）等识别抗体，应用范围包括Western blot、免疫组化、免疫荧光和ELISA等。另外，Rockland也生产特别齐全的二抗，包括纯化、生物素、HRP/ALP、荧光标记二抗，应用十分广泛。

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