MPO

亚型 ：IgG

形态 ：液体

保存条件 ：-20℃

克隆性 ：多克隆

标记物 ：无

适应物种 ：HMR

保质期 ：一年

抗原来源 ：兔

供应商 ：万类生物

宿主 ：兔

应用范围 ：WB,IHC

浓度 ：>1 mg/ml

靶点 ：MPO

抗体英文名 ：MPO antibody

抗体名 ：MPO 抗体

规格 ：50μl(>50μg)

产品概述

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. In normal neutrophils, MPO is expressed as a dimer. Calreticulin, a calcium-binding protein residing in the ER, interacts specifically with fully glycosylated apopro-MPO. MPO is expressed at high levels in circulating neutrophils and monocytes but is not detectable in microglia, brain-specific macrophages or normal brain tissue.

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