MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

MCT1-IN-3

CAS No. : 2878360-80-4

MCE 国际站：MCT1-IN-3

产品活性：MCT1-IN-3 是一种单羧酸转运蛋白 1 (MCT1) 抑制剂，IC₅₀ 值为 81.0 nM。MCT1-IN-3 还对多药转运蛋白 ABCB1 具有显著的抑制作用。MCT1-IN-3 可用于癌症的研究。

研究领域：Membrane Transporter/Ion Channel

作用靶点：Monocarboxylate Transporter  |  P-glycoprotein

In Vitro: MCT1-IN-3 (compound 24) has inhibitory activity for MCT1 with an IC₅₀ value of 81.0 nM.
MCT1-IN-3 has great antiproliferative activities against the MCT1-expressing cancer cell lines A-549 and MCF-7 with GI₅₀ values of 20 μM and 15.1 μM, respectively.
MCT1-IN-3 (5 μM; 24 h) leads to cancer cell cycle arrest as well as apoptosis.
MCT1-IN-3 (1.0, 2.0, 3.5, and 5.0 μM) shows to sensitize these cancer cells toward an antineoplastic agent.
MCT1-IN-3 has also significant inhibitory power against the multidrug transporter ABCB1 and shows to reverse ABCB1-mediated multidrug resistance (MDR) .

相关产品：AZD3965  |  Verapamil  |  Elacridar  |  AR-C155858  |  Glibenclamide  |  Tariquidar  |  Syrosingopine  |  VB124  |  Zosuquidar trihydrochloride  |  CP-100356 hydrochloride  |  Piperine  |  Risperidone  |  α-Cyano-4-hydroxycinnamic acid  |  BAY-8002  |  AZD0095  |  Limonin  |  Valspodar  |  MSC-4381  |  Trifluoperazine dihydrochloride  |  7ACC2  |  7ACC1  |  Atazanavir sulfate  |  Paris saponin VII  |  Encequidar  |  Solamargine  |  Silychristin  |  Dofequidar fumarate

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds