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靶点 :ITM2C
应用范围 :WB
宿主 :Rabbit
适应物种 :Human;Mouse;Rat
保质期 :一年
供应商 :北京索莱宝科技有限公司
克隆性 :Polyclonal Antibody
保存条件 :Store at -20℃. Avoid freeze / thaw cycles.
亚型 :IgG
免疫原 :Recombinant protein of human ITM2C
规格 :50ul
产品简介中文名称 | 整合膜蛋白2C抗体 |
靶标 | ITM2C |
别名 | BRI3; BRICD2C; BRICHOS domain containing 2C; Cerebral protein 14; CT-BRI3; E25; E25C; Integral membrane protein 2C; Integral membrane protein 3; Itm2c; ITM2C_HUMAN; ITM3; NPD018; Transmembrane protein BRI3; |
背景资料 | Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity). |
Swiss Prot | Q9NQX7 |
亚细胞定位 | Cell membrane Cytoplasm |
宿主 | Rabbit |
克隆类型 | Polyclonal Antibody |
亚型 | IgG |
预测交叉反应 | Bovine;Rabbit;Pig;Monkey;Gorilla |
蛋白分子量 | 61/68/70kDa |
实际分子量 | 70kDa |
稀释比例 | WB 1:1000-3000. |
免疫原 | Recombinant protein of human ITM2C |
Public Immunogen Range | 1-200aa |
纯化方法 | Affinity purification |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
保存 | Store at -20℃. Avoid freeze / thaw cycles. |
交叉反应 | Human;Mouse;Rat |
应用 | WB |
规格 | 50ul 100ul |
单位 | 支 |
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Western blot analysis with ITM2C antibody diluted at 1:2000;Lane: HEK293.
北京索莱宝科技有限公司
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入驻年限:12年