Dolastatin 10,110417-88-4

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抑制剂描述：

产品名称：Dolastatin 10

产品别名：见爱必信官网

英文别名：Dolastatin 10

靶点：Microtubule/Tubulin

CAS：110417-88-4

纯度：

外观：见爱必信官网

保存方法：Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

描述：Angiotensin II human is a vasoconstrictor that acts on the AT1 and the AT2 receptor.

溶解性：10 mM in DMSO

体外研究：

Dolastatin 10 is a unique pentapeptide that isolated from the sea hare Dolabella auricularia. These in vitro data are quite comparable to those of Dolastatin 10 and Auristatin PE, each of which has GI50 values of 10−5-10−6 μg/mL (10−2-10−3 nM) against a similar minipanel of human cell lines. The antibody-drug conjugate (ADC) comprises the anti-CD30 monoclonal antibody cAC10 conjugated to the cytotoxic agent monomethyl auristatin E (MMAE), a synthetic analog of the tubulin polymerization inhibitor Dolastatin 10.

体内研究：

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