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保存条件 :Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
库存 :99
供应商 :爱必信(上海)生物科技有限公司
CAS号 :55-97-0
规格 :500mg/200mg/100mg/50mg
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抑制剂描述: 产品名称:Hexamethonium Bromide 产品别名:见爱必信官网 英文别名:Hexamethonium Bromide 靶点:AChR CAS:55-97-0 纯度:>98% 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述: Hexamethonium Bromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia. 溶解性:DMSO :18.1 mg/mL (50 mM) 体外研究: Hexamethonium Bromide is effective against Ach and carbachol (CCh) on the amplitude of endplate responses of rat omohyoid muscle with EC50 of 300 μM and 100 μM, respectively. Hexamethonium Bromide (50-200 μM) causes an increase in the amplitude of nerve-evoked endplate currents (e.p.cs) recorded in the presence of 0.6 μM tubocurarine. Hexamethonium Bromide is also a weak inhibitor of acetylcholinesterase activity in rat muscle homogenates with EC50 of 1.5 mM. Hexamethonium Bromide (200 μM) decreases the time constant of decay of both endplate currents (e.p.cs) (by ~25%) and miniature endplate currents (m.e.p.cs) (by ~20%) in the rat hemi-diaphragm muscle. At low frequencies of stimulation (0.5-2 Hz), Hexamethonium Bromide (200 μM) increases e.p.c. quantal content by 30-40%. 体内研究: 产品信息订购:
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