Phospho-STAT3-Y705 Rabbit pAb

抗体英文名 ：Phospho-STAT3-Y705 Rabbit pAb

应用范围 ：WB

宿主 ：Rabbit

库存 ：200

供应商 ：武汉爱博泰克生物科技有限公司

保存条件 ：Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

规格 ：50 μL

产品名称：	Phospho-STAT3-Y705 Rabbit pAb
货号：	AP0070
背景：	The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors; STAT family members are phosphorylated by the receptor associated kinases; and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs; EGF; IL5; IL6; HGF; LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli; and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
别名：	ADMIO; ADMIO1; APRF; HIES; STAT3; Stat3
宿主：	Rabbit
反应物种：	Human; Mouse
验证应用：	WB
免疫原：	A synthetic phosphorylated peptide around Y705 of human Phospho-STAT3-Y705 (NP_644805.1).
基因ID：	6774
存储缓冲液：	Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide;50% glycerol;pH7.3.
图片：	Western blot - Phospho-STAT3-Y705 Rabbit pAb (AP0070)
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