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SIRT2-IN-9

CAS No. : 522650-91-5

MCE 国际站：SIRT2-IN-9

产品活性：SIRT2-IN-9 (compound 12) 是 SRIT2 的选择性抑制剂，IC₅₀ 值为 1.3 μM。SIRT2-IN-9 抑制 MCF-7 乳腺癌细胞的增殖活性。SIRT2-IN-9 可用于癌症的研究。

研究领域：Cell Cycle/DNA Damage  |  Epigenetics

作用靶点：Sirtuin

In Vitro: SIRT2-IN-9 (1-100 μM; 15 min) dose-dependently inhibits SRIT2 with an IC₅₀ value of 1.3 μM, and inhibits SRIT1 and SRIT3 with IC₅₀s ＞300 μM.SIRT2-IN-9 (0-50 μM; 72 h) affects cell viability of MCF-7 cells.SIRT2-IN-9 (0-50 μM; 6 h) affects acetylation of α-tubulin protein.

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