小鼠抗ALOX15单克隆抗体

形态 ：液体

保存条件 ：冷冻（-20℃）避光

克隆性 ：多克隆

适应物种 ：小鼠

保质期 ：一年

抗原来源 ：ALOX15

库存 ：200

供应商 ：上海酶联生物科技有限公司

宿主 ：Mouse

应用范围 ：仅供科研使用

抗体英文名 ：Anti-ALOX15mousemonoclonalantibody

抗体名 ：小鼠抗ALOX15单克隆抗体

规格 ：100ul

中文名称： 小鼠抗ALOX15单克隆抗体

英文名称：Anti-ALOX15mousemonoclonalantibody

别名：12-LOX;15-LOX-1;15LOX-1

相关类别：一抗

储存：冷冻（-20℃）避光

宿主：Mouse

抗原：ALOX15

反应种属：Human

标记物：Unconjugate

克隆类型：mousemonoclonal

技术规格

Background:	Non-hemeiron-containingdioxygenasethatcatalyzesthestereo-specificperoxidationoffreeandesterifiedpolyunsaturatedfattyacidsgeneratingaspectrumofbioactivelipidmediators.Convertsarachidonicacidinto12-hydroperoxyeicosatetraenoicacid/12-HPETEand15-hydroperoxyeicosatetraenoicacid/15-HPETE.Alsoconvertslinoleicacidto13-hydroperoxyoctadecadienoicacid.Mayalsoacton(12S)-hydroperoxyeicosatetraenoicacid/(12S)-HPETEtoproducehepoxilinA3.Probablyplaysanimportantroleintheimmuneandinflammatoryresponses.Throughtheoxygenationofmembrane-boundphosphatidylethanolamineinmacrophagesmayfavorclearanceofapoptoticcellsduringinflammationbyresidentmacrophagesandpreventanautoimmuneresponseassociatedwiththeclearanceofapoptoticcellsbyinflammatorymonocytes.Inparallel,mayregulateactinpolymerizationwhichiscrucialforseveralbiologicalprocesses,includingmacrophagefunction.Mayalsoregulatemacrophagefunctionthroughregulationoftheperoxisomeproliferatoractivatedreceptorsignalingpathway.Finally,itisalsoinvolvedinthecellularresponsetoIL13/interleukin-13.Inadditiontoitsroleintheimmuneandinflammatoryresponses,mayplayaroleinepithelialwoundhealinginthecorneamaybethroughproductionoflipoxinA4.Mayalsoplayaroleinendoplasmicreticulumstressresponseandtheregulationofbonemass.
Applications:	WB,IHC,IF,FC
Nameofantibody:	ALOX15
Immunogen:	FusionproteinofhumanALOX15
Fullname:	arachidonate15-lipoxygenase(ALOX15)
Synonyms:	12-LOX;15-LOX-1;15LOX-1
SwissProt:	P16050
IHCpositivecontrol:	adenocarcinomaofhumanendometriumtissue
IHCRecommenddilution:	30-150
WBPredictedbandsize:	75kDa
WBPositivecontrol:	PC12,MCF-7celllysates
WBRecommendeddilution:	200-1000