现货 干细胞专用基底膜基质胶Cultrex Stem Cell Qualified Reduced Growth Factor Basement Membrane Extract，replacement of 354277

供应商 ：R&D

库存 ：4

英文名 ：Cultrex® Stem Cell Qualified Reduced Growth Factor Basement Membrane Extract, PathClear®

运输方式 ：干冰运输

规格 ：10ml/5ml

R&D Systems 提供高品质的 Cultrex 系列基质胶。其中减生长因子的基质胶3434-010-2已被证明可以为胚胎干细胞（HESC）和诱导多能干细胞（IPSC）提供有效的无饲养层表面。

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商品简介：

Cultrex Stem Cell Qualified Reduced Growth Factor Basement Membrane Extract Summary

Cultrex Stem Cell Qualified Reduced Growth Factor Basement Membrane Extract (RGF BME) has been shown to provide an effective feeder-free surface for the attachment and maintenance of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) in culture.

Key Benefits

• Qualified to support the culture of pluripotent stem cell
• Supports human iPSC and ESC expansion and differentiation
• Reduced growth factor formulation provides a more defined culture system
• Quality controlled for performance consistency

Why Use Cultrex Stem Cell Qualified RGF BME?

Cultrex Stem Cell Qualified Reduced Growth Factor Basement Membrane Extract (RGF BME) is a soluble form of basement membrane purified from Engelbreth-Holm-Swarm (EHS) tumor. This extract provides a natural extracellular matrix hydrogel that polymerizes at 37°C to form a reconstituted basement membrane. Cultrex Stem Cell Qualified RGF BME has been shown to provide an effective feeder-free surface for the attachment and maintenance of undifferentiated human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs). It is useful for promoting the expansion of pluripotent stem cells or for the study of stem cell differentiation.

Basement membranes are continuous sheets of specialized extracellular matrix that form an interface between endothelial, epithelial, muscle, or neuronal cells and their adjacent stroma and that play an essential role in tissue organization by influencing cell adhesion, migration, proliferation, and differentiation. The major components of BME include laminin, collagen IV, entactin, and heparin sulfate proteoglycans.

Cultrex干细胞合格的减少生长因子基膜提取物（RGF BME）已被证明为培养中的人类胚胎干细胞（HESC）和诱导多能干细胞（IPSC）的附着和维持提供了有效的无饲养层表面。

主要优点

•已验证可用于多能干细胞的培养

•支持人类iPSC和ESC细胞的扩增和分化

•减少生长因子配方提供了更明确的培养体系

•确保批次间性能一致性的质量控制

为什么使用Cultrex干细胞专用基质胶？

Cultrex干细胞鉴定的减少生长因子基底膜提取物（RGF BME）是从Engelbreth Holm Swarm（EHS）肿瘤中纯化得到的可溶形式的基底膜。该提取物提供了一种天然的细胞外基质水凝胶，在37°C下聚合形成重组基膜。Cultrex干细胞专用基质胶已被验证可用于为未分化人类胚胎干细胞（HESC）和诱导多能干细胞（IPSC）的附着和维持提供了有效的无饲养层表面。它有助于促进多能干细胞的扩增或干细胞分化的研究。

基底膜是一种连续的特殊细胞外基质，在内皮细胞、上皮细胞、肌肉细胞或神经元细胞及其相邻基质之间形成界面，通过影响细胞粘附、迁移、增殖和分化在组织组织中发挥重要作用。BME的主要成分包括层粘连蛋白、IV型胶原、戊聚糖和硫酸肝素蛋白多糖等。