Proteasome 20S beta 7 (PSMB7) Mouse Monoclonal Antibody [Clone ID: LBI1E1]

靶点 ：PSMB7

应用范围 ：WB 1:500~2000, IHC 1:150

宿主 ：Mouse

适应物种 ：Human, Monkey, Mouse, Rat

保质期 ：1-2年

供应商 ：安诺伦（北京）生物科技有限公司

标记物 ：Unconjugated

克隆性 ：Monoclonal Antibody

保存条件 ：Stable for 1 year at -20°C from date of shipment. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

形态 ：Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

亚型 ：IgG1

免疫原 ：Human recombinant protein fragment corresponding to amino acids 58-277 of human PSMB7(NP_002790) produced in E.coli.

规格 ：100 ug

别名：Z

产品概述：Carrier-free (BSA/glycerol-free) PSMB7 mouse monoclonal antibody, clone LBI1E1

总结：The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit). [provided by RefSeq]