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保质期 ：有效期1年
保存条件 ：-20℃至-80℃保存
英文名 ：Recombinant Rat Interleukin-33 (Rat IL-33)
CAS号 ：点击查看
库存 ：大量
供应商 ：翌圣生物科技（上海）股份有限公司
规格 ：10 μg
Product Information
| Product Name |
Cat# |
Size |
Price（¥） |
| Recombinant Rat Interleukin-33 (Rat IL-33) |
90180ES10 |
10 μg |
1,855 |
| 90180ES60 |
100 μg |
13,615 |
|
| 90180ES76 |
500 μg |
35,395 |
Product Description
IL-33 (Interleukin-33) is released from physically damaged or necrotic cells. It triggers Th2-biased immune cell activation at sites of inflammation as well as regulatory T cell and M2 macrophage expansion. It additionally induces angiogenesis, promotes tumor cell migration and invasion, limits cardiac myocyte hypertrophy, and limits the development of atherosclerotic plaques. IL-33 signals through a receptor complex composed of ST2 and IL-1 RAcP. IL-1 RAcP also associates with IL-1 RI, IL-1 RII, IL-1 R6, and SCF R/c-kit. Soluble isoforms of ST2 and IL-1 RAcP function as decoy receptors that regulate IL-33 bioactivity.
Product Properties
| Synonyms |
IL-33 |
| Accession |
|
| GeneID |
|
| Source |
E.coli-derived Rat IL-33, Ser109-Met264. |
| Molecular Weight |
Approximately 17.4 kDa. |
| AA Sequence |
SIQGTSLLTE SCALSTYNDQ SVSFVLENGC YVINVEDCGK NQEKDKVLLR YYESSFPAQS GDGVDGKKLM VNMSPIKDTD IWLNANDKDY SVELQKGDVS PPDQAFFVLH KKSSDFVSFE CKNLPGTYIG VKDNQLALVE ENDESCNNIM FKLSKM |
| Tag |
None |
| Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Purity |
> 95% by SDS-PAGE and HPLC analyses. |
| Biological Activity |
The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 0.5 ng/mL, corresponding to a specific activity of > 2.0 × 106 IU/mg. Fully biologically active when compared to standard. |
| Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
| Formulation |
Lyophilized from a 0.2 µm filtered concentrated solution in 20 mM Tris, 300 mM NaCl, pH 8.5. |
| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only!
HB220425
翌圣生物科技（上海）股份有限公司
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入驻年限：17年
