p63 (TP63) Mouse Monoclonal Antibody [Clone ID: LBI2A7]

靶点 ：TP63

浓度 ：1 mg/ml

应用范围 ：WB 1:500

宿主 ：Mouse

适应物种 ：Human, Mouse, Rat

保质期 ：1-2年

供应商 ：安诺伦（北京）生物科技有限公司

标记物 ：Unconjugated

克隆性 ：Monoclonal Antibody

保存条件 ：Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

形态 ：PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

亚型 ：IgG1

免疫原 ：Synthetic peptide corresponding to the N-terminus of Human P40 (ΔNp63) (NP_001108452) conjugated to KLH. The exact sequence is proprietary.

规格 ：100 ul/30 ul

别名：AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; p40; p51; p53CP; p63; p73H; p73L; RHS; SHFM4

产品概述：p40 mouse monoclonal antibody,clone LBI2A7

总结：This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008]