GFI1 Mouse Monoclonal Antibody [Clone ID: LBI6E8]

靶点 ：GFI1

浓度 ：1 mg/ml

应用范围 ：WB 1:2000, IHC 1:150

宿主 ：Mouse

适应物种 ：Human, Mouse, Rat

保质期 ：1-2年

供应商 ：安诺伦（北京）生物科技有限公司

标记物 ：Unconjugated

克隆性 ：Monoclonal Antibody

保存条件 ：Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

形态 ：PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

亚型 ：IgG1

免疫原 ：Human recombinant protein fragment corresponding to amino acids 1-180 of human GFI1(NP_005254) produced in E.coli.

规格 ：100 ul/30 ul

别名：GFI-1; GFI1A; SCN2; ZNF163

产品概述：GFI1 mouse monoclonal antibody, clone LBI6E8

总结：This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]