NF-κB2 Rabbit mAb (AMR13126N)

靶点 ：CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p100; p49/p100; p52

浓度 ：Affinity purification

宿主 ：Rabbit

适应物种 ：Human, Mouse, Rat

保质期 ：1-2年

供应商 ：安诺伦（北京）生物科技有限公司

保存条件 ：Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

形态 ：形式：Liquid 储存溶液：Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

亚型 ：IgG

免疫原 ：A synthesized peptide derived from human NF-κB2.

规格 ：50 µl/100 µl/200 µl

分子量：Calculated MW: 47kDa/96kDa
Observed MW: 120KDa

细胞定位：Cytoplasm, Nucleus

稀释方法：WB 1:500 - 1:2000
IHC 1:50 - 1:200

总结：This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]