ATP2B1 Rabbit pAb (APR30311N)

靶点 ：PMCA1; PMCA1kb

浓度 ：Affinity purification

应用范围 ：WB (Mus musculus)

宿主 ：Rabbit

适应物种 ：Human, Mouse, Rat

保质期 ：1-2年

供应商 ：安诺伦（北京）生物科技有限公司

保存条件 ：Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

形态 ：形式：Liquid 储存溶液：Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

亚型 ：IgG

免疫原 ：A synthetic peptide corresponding to a sequence within amino acids 250-350 of human ATP2B1 (NP_001673.2).

规格 ：50 µl/100 µl/200 µl

分子量：Observed MW: 140kDa

稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:200

总结：The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]