HDAC7 Rabbit pAb (APR23128N)

靶点 ：HDAC7; HD7; HD7A; HDAC7A

浓度 ：Affinity purification

宿主 ：Rabbit

适应物种 ：Human, Rat

保质期 ：1-2年

供应商 ：安诺伦（北京）生物科技有限公司

保存条件 ：Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

形态 ：形式：Liquid 储存溶液：Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

亚型 ：IgG

免疫原 ：A synthetic peptide corresponding to a sequence within amino acids 400-500 of human HDAC7 (NP_056216.2).

规格 ：50 µl/100 µl/200 µl

分子量：Calculated MW: 46-66kDa, 99-108kDa

细胞定位：Cytoplasm, Nucleus

稀释方法：IHC 1:50 - 1:200
IF 1:50 - 1:200

总结：Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.