SPG11 Rabbit pAb (APR17951N)

靶点 ：SPG11; ALS5; CMT2X; KIAA1840; spatacsin

浓度 ：Affinity purification

宿主 ：Rabbit

适应物种 ：Human

保质期 ：1-2年

供应商 ：安诺伦（北京）生物科技有限公司

保存条件 ：Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

形态 ：形式：Liquid 储存溶液：Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

亚型 ：IgG

免疫原 ：Recombinant fusion protein containing a sequence corresponding to amino acids 550-750 of human SPG11 (NP_079413.3).

规格 ：50 µl/100 µl/200 µl

分子量：Calculated MW: 236kDa/266kDa/278kDa
Observed MW: 280kDa

细胞定位：Cytoplasm, Membrane, Multi-pass membrane protein, Nucleus, cytosol

稀释方法：WB 1:200 - 1:2000

总结：The protein encoded by this gene is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene.