白介素1α/IL-1α抗体价格_品牌:YLKBIO-丁香通官网

供应商：优利科（上海）生命科学有限公司

库存：100

靶点：详询

级别：科研

目录编号：/

克隆性：多克隆

抗原来源：详见说明书

保质期：1年

抗体英文名：Anti-IL-1 Alpha

抗体名：IL-1 Alpha抗体

标记物：详询

宿主：兔

适应物种：/

免疫原：KLH conjugated synthetic peptide derived from human IL-1 Alpha

亚型：IgG

形态：Lyophilized or Liquid

应用范围：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

保存条件：-20℃

浓度：1mg/ml

规格：详询

英文名称 Anti-IL-1 Alpha

中文名称白介素1α/IL-1α抗体

别名 interleukin-1 alpha; Hematopoietin 1; IL 1 alpha; IL 1; IL 1A; Il-1a; IL1; IL1A; IL1F1; ilia; Interleukin 1 alpha; Interleukin 1 alpha precursor; Interleukin1 alpha; Preinterleukin 1 alpha; Pro interleukin 1 alpha; Prointerleukin 1 alpha.

浓度 1mg/1ml

规格 0.1ml/100μg 0.2ml/200μg 1ml/1mg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human

产品类型一抗

研究领域心血管细胞生物免疫学

蛋白分子量 predicted molecular weight: 17, 31kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human IL-1 Alpha

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin 1 alpha (IL1 alpha) and interleukin 1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.

Function : Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Subunit : Monomer.

Subcellular Location : Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.

Similarity : Belongs to the IL-1 family.

Database links : UniProtKB/Swiss-Prot: P01583.1