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英文名 :Human Amyloid beta A4 Protein (诊断原料,神经生物学)
Recombinant Human Amyloid beta A4 Protein
Catalog #: DRA20 Derived From: Human Cells
Description:
Recombinant Human Amyloid β A4 Protein/APP is produced by our Mammalian expression system and the target gene encoding Leu18-Leu305 is expressed with a 6His tag at the C-terminus.
Accession: P05067-2
Names(Known as):Amyloid Beta A4 Protein; ABPP; APPI; APP; Alzheimer Disease Amyloid Protein; CerebralVascularAmyloid Peptide; CVAP; PreA4; Protease Nexin-II; PN-II; APP
Quality Control:
Mol Mass: 33.6kDa AP Mol Mass: 50kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Formulation:
Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:
The product is shipped on dry ice pack.
Upon receipt, store it immediately at the temperature listed below.
Storage:
Reconstituted protein solution should be stored at ≤ -20°C.
Purification:
Affinity purification chromatography.
Immunoreactivity:
N.A.
Application:
Immunogen, calibrator or standard.
Background:
Amyloid β A4 Protein (APP) is an integral membrane protein that belongs to the APP family. APP contains one BPTI/Kunitz inhibitor domain. APP is expressed in all fetal tissues, with the highest expression levels observed in the brain, kidney, heart, and spleen. APP is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion, and axonogenesis. APP plays a role in cell mobility and transcription regulation through protein-protein interactions. APP also promotes transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Mutations in APP are associated with Alzheimer's disease.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY
苏州近岸蛋白质科技股份有限公司
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入驻年限:13年