Anti-PTK2B Polyclonal Antibody

免疫原 ：Recombinant protein of human PTK2B

亚型 ：IgG

保存条件 ：Store at -20°C. Avoid freeze / thaw cycles.

供应商 ：北京索莱宝科技有限公司

宿主 ：Rabbit

应用范围 ：IHC

靶点 ：PTK2B

规格 ：50ul

Anti-PTK2B Polyclonal Antibody

产品简介

英文名称	Anti-PTK2B Polyclonal Antibody
靶标	PTK2B
别名	PTK2B;CADTK;CAKB;FADK2;FAK2;PKB;PTK;PYK2;RAFTK;Pyk2
宿主	Rabbit
稀释比例	IHC 1:50-200.
Gene ID	2185
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	Q14289
蛋白分子量	111/116kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm Nucleus
免疫原	Recombinant protein of human PTK2B
亚型	IgG
纯化方法	Affinity purification
背景资料	This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.
Public Immunogen Range	660-1010aa
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Immunohistochemistry of paraffin-embedded Human colorectal cancer with PTK2B antibody diluted at 1:100

Immunohistochemistry of paraffin-embedded Human endometrial cancer with PTK2B antibody diluted at 1:100