抑制蛋白结构域蛋白4抗体

供应商 ：优利科（上海）生命科学有限公司

库存 ：96

靶点 ：/

级别 ：科研

目录编号 ：KT1360

克隆性 ：多克隆

抗原来源 ：/

保质期 ：1年

抗体英文名 ：ARRDC4

抗体名 ：Rabbit Anti-ARRDC4 antibody

标记物 ：详询

宿主 ：兔

适应物种 ：predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Sheep

免疫原 ：KLH conjugated synthetic peptide derived from human ARRDC4: 201-330/418

亚型 ：IgG

形态 ：Liquid

应用范围 ：ELISA=1:5000-10000

保存条件 ：-20℃

浓度 ：1mg/ml

规格 ：50ul

中文名称：抑制蛋白结构域蛋白4抗体

英文名称：ARRDC4

别    名：ARRDC 4; Arrestin domain containing protein 4; ARRD4_HUMAN.  

分 子 量：45 kDa

细胞定位：细胞浆 细胞膜 

纯化方法：affinity purified by Protein A

储 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.





产品介绍：ARRDC4 belongs to the arrestin family. The arrestins are a family of proteins that are important for regulating signal transduction within cells. Arrestins are part of a conserved two step mechanism for regulating the activity of G-protein coupled receptors (GPCRs). In response to a stimulus, GPCRs activate a heterotrimeric G protein. In order to turn off this response, or adapt to a constant stimulus, activated receptors need to be silenced. The first step is phosphorylation by a class of serine/threonine kinases called G protein coupled receptor kinases (GRKs). This phosphorylation specifically marks the activated receptor for arrestin binding. Once arrestin is bound to the receptor it is unable to signal further. Recent research continues to expand the known actions of arrestins, which can bind to other classes of receptors and can directly activate signaling pathways on their own. Different arrestins (visual arrestin (or Arrestin 1), beta-arrestin 1 (or Arrestin 2) and beta-arrestin 2 (or Arrestin 3) can reduce the activity of their target GPCRs in several different ways.

Similarity:
Belongs to the arrestin family.

SWISS:
Q8NCT1

Gene ID:
91947

注意：
所提供的本产品仅供研究使用，不得用于人类、治疗或诊断应用。