醛固酮还原酶家族1成员D1抗体

供应商 ：优利科（上海）生命科学有限公司

库存 ：55

靶点 ：/

级别 ：科研

目录编号 ：KT0755

克隆性 ：多克隆

抗原来源 ：/

保质期 ：1年

抗体英文名 ：AKR1D1

抗体名 ：Rabbit Anti-AKR1D1 antibody

标记物 ：详询

宿主 ：兔

适应物种 ：Rat, (predicted: Human, Mouse, Dog, Cow, Horse, Rabbit, )

免疫原 ：KLH conjugated synthetic peptide derived from human AKR1D1: 101-200/326

亚型 ：IgG

形态 ：Liquid

应用范围 ：ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

保存条件 ：-20℃

浓度 ：1mg/ml

规格 ：50ul

中文名称：醛固酮还原酶家族1成员D1抗体

英文名称：AKR1D1

别    名：3-oxo-5-beta-steroid 4-dehydrogenase; 3o5bred; AK1D1_HUMAN; AKR1D1; aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase); Aldo keto reductase family 1 member D1; Aldo-keto reductase family 1 member D1; CBAS2; Delta(4) 3 ketosteroid 5 beta reductase; Delta(4) 3 oxosteroid 5 beta reductase; Delta(4)-3-ketosteroid 5-beta-reductase; Delta(4)-3-oxosteroid 5-beta-reductase; SRD5B1; steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1); steroid 5 beta reductase.  

货号：YLK-KT0755

分 子 量：37kDa

细胞定位：细胞核 细胞浆 

纯化方法：affinity purified by Protein A

储 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.




 

产品介绍：有效催化黄TI酮、雄烯二酮、17-α-羟基孕酮和睾酮还原为 5-β-还原代谢物。 胆汁酸中间体 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one 和 7-alpha-hydroxy-4-cholesten-3-one 也可以作为底物。

Function:
Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Highly expressed in liver. Expressed in testis and weakly in colon.

注意：
所提供的本产品仅供研究使用，不得用于人类、治疗或诊断应用。