产品详情
文献和实验
相关推荐
保质期 ：有效期1年
保存条件 ：-20℃至-80℃保存
CAS号 ：点击查看
供应商 ：翌圣生物科技(上海)股份有限公司
库存 ：大量
英文名 ：Recombinant Mouse Granulocyte-Macrophage Colony Stimulating Factor (Mouse GM-CSF)
规格 ：5ug
Product Information
| Product Name |
Cat# |
Size |
Price（¥） |
| Recombinant Mouse Granulocyte-Macrophage Colony Stimulating Factor (Mouse GM-CSF) |
91108ES08 |
5 μg |
815.00 |
| 91108ES60 |
100 μg |
8515.00 |
|
| 91108ES76 |
500 μg |
22115.00 |
Product Description
Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) is a powerful growth and differentiation factor which acts on hematopoietic progenitor cells and also activates differentiated granulocytes and macrophages. The 22 kDa glycosylated GMCSF, similar to IL3 and IL5, is a cytokine with a core of four bundled alpha -helices. Mature human GMCSF shares 63%70% amino acid sequence identity with canine, feline, porcine, and rat GMCSF and 54% with mouse GMCSF. GM-CSF has been and is still widely used as an adjuvant in clinical trials of vaccination with autologous tumor cells, peptides and/or dendritic cells in a variety of human neoplasms. The effects of GM-CSF on HIV-1 replication in primary monocytes and macrophages, and in related cell lines, have demonstrated augmentation of HIV-1 expression in vitro.
Product Properties
| Synonyms |
Granulocyte/Macrophage Colony-Stimulating Factor, GM-CSF, CSF-2, MGI-1GM, Pluripoietin-α |
| Accession |
|
| GeneID |
|
| Source |
E.coli-derived mouse GM-CSF protein, Ala18-Lys141. |
| Molecular Weight |
Approximately 14.1 kDa. |
| AA Sequence |
APTRSPITVT RPWKHVEAIK EALNLLDDMP VTLNEEVEVV SNEFSFKKLT CVQTRLKIFE QGLRGNFTKL KGALNMTASY YQTYCPPTPE TDCETQVTTY ADFIDSLKTF LTDIPFECKK PGQK |
| Tag |
None |
| Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Purity |
> 98% by SDS-PAGE and HPLC analyses. |
| Biological Activity |
The ED50 as determined by a cell proliferation assay using murine FDC-P1 cells is less than 0.05 ng/mL, corresponding to a specific activity of > 2.0 × 107 IU/mg. Fully biologically active when compared to standard. |
| Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
| Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
Avoid repeated freeze-thaw cycles.
For your safety and health, please wear lab coats and disposable gloves for operation.
For research use only.
HB220210
翌圣生物科技（上海）股份有限公司
品牌商实名认证
钻石会员
入驻年限：17年
