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保存条件 :-20°C(避免反复冻融)
保质期 :12个月
英文名 :Human TMEM119/ Transmembrane protein 119 Protein
库存 :现货
供应商 :伊艾博(武汉)科技股份有限公司
CAS号 :-
规格 :50ug/100ug/200ug/0.5mg/1mg
别名:Osteoblast induction factor,OBIF,PSEC0199,UNQ731/PRO1415序列号:Q4V9L6
来源:E.coli
种属:Human
标签:His
纯度:>9% by SDS-PAGE
浓度:Reconstitution Dependent
形态:Liquid
应用:ELISA、Western Blot、Antigen Protein
存储缓冲液:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:Store at -20°C. (Avoid repeated freezing and thawing.)
通用注释
亚单元:Interacts with SMAD1, SMAD5 and RUNX2.
功能:Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts (PubMed:20025746). May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Upregulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation.
亚细胞位置: Cell membrane Single-pass type I membrane protein Cytoplasm Endoplasmic reticulum membrane
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入驻年限:3年