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保质期 ：有效期1年
保存条件 ：-20℃至-80℃保存
CAS号 ：点击查看
供应商 ：翌圣生物科技(上海)股份有限公司
库存 ：大量
英文名 ：Recombinant Rat Interleukin-2 (Rat IL-2)
规格 ：5 μg
Product Information
| Product Name |
Cat# |
Size |
Price（¥） |
| Recombinant Rat Interleukin-2 (Rat IL-2) |
90167ES08 |
5 μg |
815.00 |
| 90167ES60 |
100 μg |
7335.00 |
|
| 90167ES76 |
500 μg |
19055.00 |
Product Description
Interleukin-2 (IL-2) is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T- cell proliferation and other fundamental functions which are essential for the immune response. The receptor for IL-2 consists of three subunits (55 kDa IL-2Rα, 75 kDa IL-2Rβ, and 64 kDa common gamma chain γc/IL-2Rγ) that are present on the cell surface in varying preformed complexes. Mature human IL-2 shares 56% and 66% amino acid sequence identity with mouse and rat IL-2, respectively. Human and mouse IL-2 exhibit cross-species activity.
Product Properties
| Synonyms |
Interleukin-2, IL-2, T-cell Growth Factor, TCGF, Aldesleukin |
| Accession |
|
| GeneID |
|
| Source |
E.coli-derived rat IL-2 protein, Ala21-Gln155. |
| Molecular Weight |
Approximately 15.5 kDa. |
| AA Sequence |
APTSSPAKET QQHLEQLLLD LQVLLRGIDN YKNLKLPMML TFKFYLPKQA TELKHLQCLE NELGALQRVL DLTQSKSFHL EDAGNFISNI RVTVVKLKGS ENKFECQFDD EPATVVEFLR RWIAICQSII STMTQ |
| Tag |
None |
| Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Purity |
> 97% by SDS-PAGE and HPLC analyses. |
| Biological Activity |
The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.2 ng/mL, corresponding to a specific activity of > 5.0 × 106 IU/mg. Fully biologically active when compared to standard. |
| Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
| Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in 10 mM sodium citrate, pH 4.0. |
| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
Avoid repeated freeze-thaw cycles.
For your safety and health, please wear lab coats and disposable gloves for operation.
For research use only!
HB220214
翌圣生物科技（上海）股份有限公司
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入驻年限：17年
