BHMT2 Polyclonal Antibody_货号:E-AB-18539_多克隆抗体

文献支持BHMT2 Polyclonal Antibody_货号:E-AB-18539_多克隆抗体

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品牌:Elabscience 品牌认证

货号:E-AB-18539

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抗体名 :BHMT2 Polyclonal Antibody_货号:E-AB-18539_多克隆抗体

抗体英文名 :BHMT2 Polyclonal Antibody

应用范围 :WB;IHC;ELISA

宿主 :Rabbit

适应物种 :Human; Mouse; Rat

保质期 :12个月

目录编号 :E-AB-18539

级别 :科研级别

库存 :999

供应商 :武汉伊莱瑞特生物科技股份有限公司

标记物 :Unconjugated

克隆性 :Polyclonal

保存条件 :Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

形态 :液体

亚型 :IgG

规格 :200μL/120μL/60μL/20μL

产品名称:BHMT2 Polyclonal Antibody
货号:E-AB-18539
Verified Samples
Verified Samples in WB:Human fetal liver,Human liver
Verified Samples in IHC:Human thyroid cancer
Dilution
WB 1:1000-1:5000, IHC 1:30-1:150, ELISA 1:5000-1:10000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human BHMT2
Abbre
BHMT2
Synonyms
Betaine homocysteine methyltransferase 2;Betaine homocysteine S methyltransferase 2;EC 2.1.1.5;FLJ20001 ;S methylmethionine homocysteine S methyltransferase BHMT2;SMM hcy methyltransferase抗体
Swissprot
Q9H2M3
Calculated MW
40 kDa
Observed MW
Refer to figures
Cellular Localization
Cytoplasmic
Concentration
0.78 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Conjugation
Unconjugated
Background
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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