文献支持CYP11B2 Polyclonal Antibody_货号:E-AB-17738_多克隆抗体

Verified Samples in WB:HepG2
Verified Samples in IHC:Human brain

WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Polyclonal

IgG

Synthetic peptide of human CYP11B2

CYP11B2

ALDOS;Aldosterone synthase;Aldosterone-synthesizing enzyme;C11B2;CYP11B2;CYPXIB2;Cytochrome P-450Aldo;Cytochrome P-450C18;Cytochrome P450 11B2;Cytochrome P450 11B2; mitochondrial;mitochondrial;P-450Aldo;P-450C18;Steroid 18-hydroxylase抗体

P19099

58 kDa

Refer to figures

Mitochondrion membrane.

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Antigen affinity purification

Cancer; Cardiovascular; Metabolism

Unconjugated

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.