文献支持TM7SF2 Polyclonal Antibody_货号:E-AB-13736_多克隆抗体

Verified Samples in WB:Mouse liver

WB 1:500-1:2000

Polyclonal

IgG

Synthetic peptide of human TM7SF2

TM7SF2

ANG1;NET47;DHCR14A抗体

O76062

46kDa

Endoplasmic reticulum,endoplasmic reticulum,endoplasmic reticulum membrane,integral component of endoplasmic reticulum membrane,Plasma Membrane,integral component of plasma membrane,Other locations:intracellular membrane-bounded organelle,organelle membrane,receptor complex

0.4 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Unconjugated

Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol to 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol and NADP+.